Imaging
Comprehensive, Turnkey Imaging and Dosimetry Services for Radiopharmaceutical Trials.
End to End Imaging Excellence
- Trial design and site setup
- CT, MRI, PET/CT, SPECT/CT and PET/MR device validation
- Multicentre PET, SPECT, CT and MRI trial management
- Image analysis panels and reading protocols
- Electronic image data transfer incl. DICOM de-identification and QC
Imaging Services
- Comprehensive equipment qualification across sites
- Standardised uptake value (SUV) harmonization
- RECIST, iRECIST, PERCIST, RANO and other advanced imaging endpoints
- Blinded Independent Central Review (BICR)
Dosimetry Expertise
- Safety and efficacy/tumour dosimetry: planar, hybrid (2.5D), or volumetric (3D)
- PET/CT, PET/MR, SPECT/CT, whole-body planar
- Preclinical through Phase III
- Consistent, central SPECT data reconstruction for multicenter trials
- Monte Carlo dose simulations
- OLINDA-, IDAC 2.1-, or IDAC-alpha-based dosimetry
- Precise and reproducible dosimetry using our in-house developed QDOSE software
Modalities
- Positron emission based: PET, PET/CT and PET/MRI
- Single photon based: SPECT, SPECT/CT and whole-body planar scintigraphy
- Cross-sectional imaging: CT, MRI
Radionuclides
- Beta emitters: i.e. Lu-177, Y-90, I-131, Cu-67
- Alpha emitters: i.e. Ac-225, Ra-223, Th-227, Pb-212, At-211
- Positron emitters: i.e. F-18, C-11, Ga-68, Zr-89, Cu-64, I-124
- Gamma emitters: i.e. Tc-99m, I-123, In-111
- Auger emitters: i.e. I-125, Tb-161